Biochemistry and Molecular Biology

    Faculty Profile

    Dr. Md. Nurshad Ali

    Assistant Professor

    Contact Information:

    • Office Address: Department of Biochemistry and Molecular Biology, Shahjalal University of Science and Technology, Sylhet-3114, Bangladesh.
    • Phone: 88-01723205092
    • Email: nali-bmb@sust.edu; nur_rubd@yahoo.com

    Biography:

    Dr. Nurshad Ali joined as a Lecturer at the Department of Biochemistry and Molecular Biology, Shahjalal University of Science and Technology in 2017. Prior to coming here, he worked as a doctoral student at Leibniz Research Centre for Working Environment and Human Factors, Dortmund, Germany. In 2016, he received his PhD. degree in Natural Sciences from the TU Dortmund University, Germany. He completed the M.Sc. and B.Sc. from the Department of Biochemistry and Molecular Biology, University of Rajshahi, Bangladesh. He also worked as a faculty member at the Department of Biochemistry and Molecular Biology, Gono University, Dhaka, Bangladesh.
    Dr. Ali’s research focuses on the area of Food Nutrition, Biomarkers of Diseases, Metabolism, Hepatology, Diabetes and Cardiovascular Disease, Toxicology, Public Health, Epidemiology and Environmental Health.

    Education:

    • Ph.D. in Natural Sciences (area of Toxicology, (2016), Leibniz Research Centre for Working Environment and Human Factors, Technical University of Dortmund, Dortmund, Germany. Dissertation title: “Biological monitoring and exposure assessment for-mycotoxins in inhabitants of Bangladesh and Germany”.
    • M.Sc. in Biochemistry and Molecular Biology, University of Rajshahi, Bangladesh. Thesis title: “Plasma Cholinesterase activity as a biomarker for arsenicosis in humans”.
    • B.Sc. in Biochemistry and Molecular Biology, University of Rajshahi, Bangladesh.

    Research Interests:

    • Biochemical Toxicology
    • Toxicity of chemicals (mycotoxins, heavy metals and others)
    • Human biomonitoring (biomarker of exposure)
    • Risk assessment of chemicals
    • Environmental Health
    • Diabetes and Cardiovascular disease
    • Public Health
    • Food, Nutrition and Metabolism
    • Hepatology and Gastroenterology
    • Epidemiology

    Active Research Project

    1. Assessment of the relationship between serum liver enzymes activity and metabolic syndrome: a study on Bangladeshi adults
    2. The relationship between serum xanthine oxidase activity and hypertension prevalence: a cross-sectional study in Bangladesh.

    Previous Research Project

    1. Prevalence of hypertension and its associated risk factors in human population- A large scale cross-sectional study in Bangladesh
    2. Biological monitoring and exposure assessment for mycotoxins in inhabitants of Bangladesh and Germany
    3. Association of circulating biomarkers with type-2 diabetes and cardiovascular diseases: A population-based study in Bangladesh.

    External Affiliations:

    • Editorial Board Member for the journal of- 1) BMC Pharmacology and Toxicology, 2) BMC Nutrition, 3) Scientific Reports-Nature, 4) PLOS ONE, 5) Frontiers in Nutrition
    • Reviewer for a number of international peer-reviewed journals.
    • Member, National Young Academy of Bangladesh
    • Member, Graduate Biochemists Association, Bangladesh

    Awards & Recognition:

    • Vice Chancellor Award 2019, Shahjal University of Science and Technology, Bangladesh.
    • Poster Award, BSBMB Conference 2018, University of Chittagong, Bangladesh.
    • Best poster award, 39th Mycotoxin Workshop 2017, Bydgoszz, Poland.
    • DAAD fellowship for doctoral studies in Germany, 2012-2016.
    • Travel Bursary Award, Eurotox congress 2015, Porto, Portugal.
    • Undergraduate Merit Scholarship 2006, Rajshahi University, Bangladesh.

    Journal Publications

    1. Mou AD, Barman Z, Hasan M, Miah R, Hafsa JM, Das Trisha A, Ali N. Prevalence of preeclampsia and the associated risk factors among pregnant women in Bangladesh. Sci Rep. 2021 Oct 29;11(1):21339. doi: 10.1038/s41598-021-00839-w.
    2. Kyei NNA, Waid JL, Ali N, Gabrysch S. Awareness, Experience, and Knowledge of Farming Households in Rural Bangladesh Regarding Mold Contamination of Food Crops: A Cross-Sectional Study. Int J Environ Res Public Health. 2021 Sep 30;18(19):10335. doi: 10.3390/ijerph181910335.
    3. Molla NH, Kathak RR, Sumon AH, Barman Z, Mou AD, Hasan A, Mahmud F, Fariha KA, Ali N. Assessment of the relationship between serum uric acid levels and liver enzymes activity in Bangladeshi adults. Sci Rep. 2021 Oct 11;11(1):20114. doi: 10.1038/s41598-021-99623-z.
    4. Islam F, Das Trisha A, Hafsa JM, Hasan A, Degen GH, Ali N. Occurrence of aflatoxin M1 in human breast milk in Bangladesh. Mycotoxin Res. 2021 Jun 22. doi: 10.1007/s12550-021-00436-w.
    5. Sumon AH, Islam F, Mohanto NC, Kathak RR, Molla NH, Rana S, Degen GH, Ali N. The Presence of Aflatoxin M1 in Milk and Milk Products in Bangladesh. Toxins (Basel). 2021 Jun 25;13(7):440. doi: 10.3390/toxins13070440.
    6. Ali N, Fariha KA, Islam F, Mishu MA, Mohanto NC, Hosen MJ, Hossain K. Exposure to air pollution and COVID-19 severity: a review of current insights, management and challenges. Integr Environ Assess Manag. 2021 Apr 29. doi: 10.1002/ieam.4435.
    7. Ali N, Sumon AH, Fariha KA, Kathak RR, Molla NH, Asaduzzaman M, Mou AD, Barman Z, Hasan M, Miah R, Islam F. Assessment of the relationship of liver enzyme activity with general and abdominal obesity in an urban population of Bangladesh. Scientific reports. 2021.11:6640. doi.org/10.1038/s41598-021-86216-z
    8. Ali N, Fariha KA, Islam F, Mohanto NC, Ahmad I, Hosen MJ, Ahmed S. Assessment of the role of zinc in the prevention of COVID-19 infections and mortality: A retrospective study in the Asian and European population. Journal of Medical Virology. 2021 doi: 10.1002/jmv.26932.
    9. Ali N, Miah R, Hasan M, Barman Z, Mou AD, Hafsa JM, Trisha AD, Hasan A, Islam F. Association between serum uric acid and metabolic syndrome: a cross-sectional study in Bangladeshi adults. Scientific Reports 2020; 10(1):7841. doi: 10.1038/s41598-020-64884-7.
    10. Ali N, Manirujjaman M, Rana S, Degen GH. Determination of aflatoxin M1 and deoxynivalenol biomarkers in infants and children urines from Bangladesh. Archives of Toxicology, 2020; 94(11):3775-3786. doi: 10.1007/s00204-020-02857-5
    11. Saadi MM, Roy MN, Haque R, Tania FA Mahmood S, Ali N. Association of microalbuminuria with metabolic syndrome: a cross-sectional study in Bangladesh. BMC Endocrine Disorders 2020; 20(1):153. doi: 10.1186/s12902-020-00634-0
    12. Ali N. Role of vitamin D in preventing of COVID-19 infection, progression and severity. Journal of infection and Public Health 2020; 13(10):1373-1380. doi.org/10.1016/j.jiph.2020.06.021
    13. Ali N, Degen GH. Biological monitoring for ochratoxin A and citrinin and their metabolites in urine samples of infants and children in Bangladesh. Mycotoxin Research 2020; 36(4):409-417 doi: 10.1007/s12550-020-00407-7
    14. Ali N, Islam F. The effects of air pollution on COVID-19 infection and mortality-a review on recent evidence. Frontiers in Public Health 2020; 8:580057. doi: 10.3389/fpubh.2020.580057
    15. Ali N. Relationship between COVID-19 infection and liver injury: a review of recent data. Frontiers in Medicine 2020; 7:458. doi: 10.3389/fmed.2020.00458.
    16. Anwar S, Araf Y, Khan AN, Ullah MA, Haque N, Sarkar B, Reshad R, Islam R, Ali N, Hosen MJ. Women’s knowledge, attitude and perceptions towards COVID-19 in lower-middle-income countries: a representative cross-sectional study in Bangladesh. Frontiers in Public Health 2020; 8:571689. doi: 10.3389/fpubh.2020.571689
    17. Ali N. Elevated level of C-reactive protein may be an early marker to predict risk for severity of COVID-19. Journal of Medical Virology 2020; 30:10.1002/jmv.26097. doi: 10.1002/jmv.26097.
    18. Rahman S, Islam S, Haque T, Kathak RR, Ali N. Association between serum liver enzymes and hypertension: a cross-sectional study in Bangladeshi adults. BMC Cardiovascular Disorders 2020; 20(1):128. doi: 10.1186/s12872-020-01411-6.
    19. Ali N. Kidney injury in COVID-19: an emerging concern to the clinician. SN Comprehensive Clinical Medicine 2020; 24:1-2. doi: 10.1007/s42399-020-00482-y.
    20. Islam S, Rahman S, Haque T, Sumon AH,Ahmed AZ, Ali N. Prevalence of elevated liver enzymes and its association with type 2 diabetes: A cross‐sectional study in Bangladeshi adults. Endocrinology Diabetes and Metabolism 2020; 3(2):e00116. doi:10.1002/edm2.116
    21. Ali N. Is SARS-CoV-2 associated with liver dysfunction in COVID-19 patients? Clinics and Research in Heapatology and Gastroenterology 2020; 44(4):e84-e86. doi.org/10.1016/j.clinre.2020.05.002
    22. Ali N, Hossain K. Liver injury in severe COVID-19 infection: current insights and challenges. Expert Review in Gastroenterology and Hepatology 2020, 44(4):e84-e86. doi:10.1080/17474124.2020.1794812
    23. Ali N, Degen GH. Citrinin biomarkers: a review of recent data and application to human exposure assessment. Archives of Toxicology. 2019; 93(11):3057-3066. doi: 10.1007/s00204-019-02570-y.
    24. Ali N. Aflatoxins in rice: Worldwide occurrence and public health perspectives. Toxicology Reports 2019; 6:1188-1197. doi: 10.1016/j.toxrep.2019.11.007.
    25. Ali N, Mahmood S, Islam F, Rahman S, Haque T, Islam S, Rahman S, Haque N, Mosaib G, Rasheda Perveen R and Khanum FA. Relationship between serum uric acid and hypertension: a crosssectional study in Bangladeshi Adults. Scientific Reports. 2019. 9(1): 9061. doi: 10.1038/s41598-019-45680-4
    26. Haque T, Rahman S, Islam S, Molla NH, Ali N. Assessment of the relationship between serum uric acid and glucose levels in healthy, prediabetic and diabetic individuals. Diabetology and Metabolic Syndrome, 2019, 11:49. doi: 10.1186/s13098-019-0446-6..
    27. Ali N, Degen GH. Biomonitoring of zearalenone and its main metabolites in urines of Bangladeshi adults. Food and Chemical Toxicology. 2019, 130:276-283. doi: 10.1016/j.fct.2019.05.036.
    28. Malir F, Louda M, Ostry V, Toman J, Ali N, Grosse Y, Malirova E, Pacovsky J, Pickova D, Brodak M, Pfohl-Leszkowicz A, Degen GH. Analyses of biomarkers of exposure to nephrotoxic mycotoxins in a cohort of patients with renal tumours. Mycotoxin Res. 2019 Jun 29. doi: 10.1007/s12550-019-00365-9.
    29. Ali N, Rahman S, Islam S, Haque T, Molla NH, Sumon AH, Kathak RR, Asaduzzaman M, Islam F, Mohanto NC, Hasnat MA, Nurunnabi SM, Ahmed S. The relationship between serum uric acid and lipid profile in Bangladeshi adults. BMC Cardiovasc Disord. 2019 Feb 21;19(1):42. doi: 10.1186/s12872-019-1026-2.
    30. Ali N, Perveen R, Rahman S, Mahmood S, Rahman S, Islam S, Haque T, Sumon AH, Kathak RR, Molla NH, Islam F, Mohanto NC, Nurunnabi SM, Ahmed S, Rahman M. Prevalence of hyperuricemia and the relationship between serum uric acid and obesity: A study on Bangladeshi adults. PLoS One. 2018 Nov 1;13(11):e0206850. doi: 10.1371/journal.pone.0206850.
    31. Ali N, Degen GH. Urinary biomarkers of exposure to the mycoestrogen zearalenone and its modified forms in German adults. Archives of Toxicology. 2018 Jul 6.doi: 10.1007/s00204-018-2261-5.
    32. Ali N, Muñoz K, Degen GH.Ochratoxin A and its metabolites in urines of German adults-An assessment of variables in biomarker analysis. Toxicology Letters 2017, 275:19-26. doi: 10.1016/j.toxlet.2017.04.013.
    33. Ali N, Blaszkewicz M, Degen GH. Determination of aflatoxin M1 in urines indicates frequent dietary exposure to aflatoxin B1 in the Bangladeshi population. International Journal of Hygiene and Environmental Health 2017 220:271-281. doi: 10.1016/j.ijheh.2016.11.002.
    34. Ali N, Mahmood S, Manirujjaman M, Perveen R, Al Nahid A, Ahmed S, Khanum FA, Rahman M. Hypertension prevalence and influence of basal metabolic rate on blood pressure among adult students in Bangladesh. BMC Public Health. 2017, 25;1858. doi: 10.1186/s12889-017-4617-9.
    35. Degen GH, Ali N, Ursula Gundert-Remy U. Preliminary data on citrinin kinetics in humans and their use to estimate citrinin exposure based on biomarkers. Toxicology Letters 2017. pii: S0378-4274(17)31418-2. doi: 10.1016/j.toxlet.2017.
    36. Ali N, Hossain K, Degen GH. Blood plasma biomarkers of citrinin and ochratoxin A exposure in young adults in Bangladesh. Mycotoxin Res. 2017 Nov 16. doi: 10.1007/s12550-017-0299-5.
    37. Ali N. Co-occurrence of citrinin and ochratoxin A in rice in Asia and its implications for human health. J Sci Food Agric. 2017 Sep 12. doi: 10.1002/jsfa.8667.Review
    38. Mahmood S, Biswas SK, Saqueeb SN, Zaman S, Manirujjaman M, Perveen R, Ali N. Vitamin D and parathyroid hormone status in female garment workers: a case- control study in Bangladesh. BioMed Research International 2017, 2017:4105375. doi: 10.1155/2017/4105375.
    39. Ali N, Blaszkewicz M, Degen GH. Assessment of deoxynivalenol exposure among Bangladesh and German adults by a biomarker based approach. Toxicology Letters 2016, 258: 20–28
    40. Ali N, Blaszkewicz M, Manirujjaman M, Degen GH. Biomonitoring of concurrent exposure to ochratoxin A and citrinin in pregnant women in Bangladesh. Mycotoxin Research 2016, 32:163-72; DOI 10.1007/s12550-016-0251-0
    41. Föllmann W, Ali N, Blaszkewicz M, Degen GH. Biomonitoring of mycotoxins in urine: Pilot study in mill workers. Journal of Toxicology and Environmental Health, Part A 2015, 79: 1015-1025
    42. Ali N, Blaszkewicz M, Alim A, Hossain K, Degen GH. Urinary biomarkers of ochratoxin A and citrinin exposure in two Bangladeshi cohorts: follow-up study on regional and seasonal influences. Archives of Toxicology 2015, DOI:10.1007/s00204-015-1654-y
    43. Ali N, Hossain K, Blaszkewicz M, Rahman M Mohanto NC, Alim A, Degen GH. Occurrence of aflatoxin M1 in urine from rural and urban adult cohorts in Bangladesh. Archives of Toxicology 2015, DOI: 10.1007/s00204-015-1601-y
    44. Ali N, Blaszkewicz M, Nahid AA, Rahman M, Degen GH. Deoxynivalenol exposure assessment for pregnant women in Bangladesh. Toxins (Basel) 2015, 7:3845–57
    45. Ali N, Blaszkewicz M, Degen GH. Occurrence of the mycotoxin citrinin and its metabolite dihydrocitrinone in urines of German adults. Archives of Toxicology 2015, 89:573–8
    46. Gerding J, Ali N, Schwartzbord J, Cramer B, Brown DL, Degen GH, Humpf HU. A comparative study of the human urinary mycotoxin excretion patterns in Bangladesh, Germany and Haiti using a rapid and sensitive LC-MS/MS approach. Mycotoxin Research 2015, 31:127–36
    47. Ali N, Blaszkewicz M, Mohanto NC, Rahman M, Alim A, Hossain K, Degen GH. First results on citrinin biomarkers in urines from rural and urban cohorts in Bangladesh. Mycotoxin Research 2015, 31: 9-16
    48. Ali N, Blaszkewicz M, Manirujjaman M, Perveen R, Nahid AA, Mahmood S, Rahman M, Hossain K, Degen GH. Biomonitoring of ochratoxin A in blood plasma and exposure assessment of adult students in Bangladesh. Molecular Nutrition and Food Research 2014, 58: 2219-2225.
    49. Huda N ,Hossain S, Rahman M, Karim MR, Islam K, Mamun AA, Hossain MI, Mohanto NC, Alam S, Aktar S, Arefin A, Ali N, Salam KA, Aziz A,Saud ZA, Miyataka H, Himeno S, Hossain K. Elevated levels of plasma uric acid and its relation to hypertension in arsenic-endemic human individuals in Bangladesh. Toxicology and Applied Pharmacology 2014 281: 11-18.
    50. Islam K, Haque A, Karim MR, Fajol A, Hossain E, Salam KA, Ali N, Saud ZA, Rahman M, Rahman M, Karim MR, Sultana P, Hossain M, Akhand AA, Miyataka H, Himeno S, Hossain K. Dose-response relationship between arsenic exposure and the serum enzymes for liver function tests in the individuals exposed to arsenic: a cross sectional study in Bangladesh. Environmental Health 2011 10:64.
    51. Karim MR, Salam KA, Hossain E, Islam K, Ali N, Haque A, Saud ZA, Yeasmin T, Hossain M, Miyataka H, Himeno S, Hossain K. Interaction between chronic arsenic exposure via drinking water and plasma lactate dehydrogenase activity. Science of the Total Environment 2010, 409: 278-83.
    52. Karim MR, Haque A, Islam K, Ali N, Salam KA, Saud ZA, Hossain E, Fajol A, Akhand AA, Himeno S, Hossain K. Protective effects of the dietary supplementation of turmeric (Curcuma longa L.) on sodium arsenite-induced biochemical perturbation in mice. Bangladesh Medical Research Council Bulletin 2010 36:82-88.
    53. Ali N, Hoque MA, Haque A, Salam KA, Karim MR, Rahman A, Islam K, Saud ZA, Khalek MA, Akhand AA, Hossain M, Mandal A, Karim MR, Miyataka H, Himeno S, Hossain K. Association between arsenic exposure and plasma cholinesterase activity: a population based study in Bangladesh. Environmental Health 2010, 9:36.

    Teaching

    • Nutritional Biochemistry
    • Environmental Biochemistry
    • Clinical Biochemistry
    • Plant Biochemistry
    • Molecular Biology

    Graduate Supervision

    1. Fifteen (15)